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Nanotoxicology Titanium Dioxide Panel - Powdered

 

Titanium dioxide, or titania, nanoparticles can be found marketed under numerous commercial manufacturing names with an extraordinary diversity of chemical properties. Two formulations of titania nanoparticles can have very different crystal lattice structures, surface coatings, solubility in media, size, and purity. A single formulation may have uses in sectors spanning from cosmetics to inks and pigments to coatings, among many others. With such a broad selection of materials for testing, the titania market can be difficult for the scientific community to navigate when trying to identify materials for testing specific hypotheses regarding nanomaterial behavior and toxicity.

nanoComposix has simplified this task by selecting panels of materials to minimize difference in formulations so the research community can focus on investigating specific hypothesis involving size and shape properties of nanoparticles.  Hydrophilic formulations of titania are highlighted in the panel for compatibility with standardized assays requiring dispersion or addition to media. Although many of the titania formulations are coated with hydrophobic materials for incorporation into cosmetics, hydrophilic materials are still applicable in the pigment and coatings markets. Hydrophilic materials were selected for the nanoComposix titania panel with size and shape related hypothesis in mind. For testing in hydrophobic environments and biological implications of titania in cosmetics, other titania materials are available upon request in small and reasonably priced quantities.

Size Panel

If you are interested in evaluating size related effects and pharmacokinetics of titania in biological systems, nanoComposix has a pre-selected panel of powdered nanoparticles that will fit your needs. These materials are commercially used as pigments and photocatylsts in paints, cosmetics, food, and plastics. Since panels come in powdered form, there is no need to be concerned over shell life, and suspension suggestions are provided with the material for wet dosing during experiments.

The materials in the titanium dioxide size panel were selected based on their dispersibility in water, size distribution, aggregation state, and crystalline structure. All samples are a rutile/anatase mix, dispersible and positively charged in aqueous media, and roughly spherical. Three different titanium dioxide samples represent the smaller size classes available on the market in the 20-35 nm size range. Although the mean diameter is similar, the size distributions are varied, and therefore, the specific surface area is almost 10-fold different between samples which makes testing hypothesis regarding surface area an interesting facet of this panel. Included in this size range is also the standard Aeroxide P25, generally considered the reference standard for comparability within the literature. Finally, on the larger size scale is a 180 nm nominal diameter anatase/rutile mix sample with a low specific surface area.

This is everything you need to test a number of hypotheses in your model system of choice.

Highlights

  • Highly characterized, commercially relevant materials
  • Particles for testing size and specific surface area differences
  • Industry standard control included
  • Dispersible in aqueous media with protocols provided